Injectafer infusions are given over a period of at least 15 minutes. With IDA, you have low hemoglobin levels. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Consult your pharmacist or local waste disposal company. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. It is very important that your doctor check you closely while you are receiving this medicine. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. (Hemoglobin is a protein thats found in red blood cells.). And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). And theyll recommend how soon after starting the drug you need to have this level checked. Injectafer should be stored between 68F to 77F (20C to 25C). For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Before taking Injectafer, talk with your doctor about your health history. It depends. I had Venofer infusions, 2 rounds now in the span of three years. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. You may report side effects to the FDA at 1-800-332-1088. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. In the US - Call your doctor for medical advice about side effects. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? (Hemoglobin is a protein thats found inside your red blood cells.). To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In one study, people were given either Injectafer or an iron replacement drug called Venofer. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. This site is intended for use only by US patients. If youre interested in finding an alternative to Injectafer, talk with your doctor. Properly discard this product when it is expired or no longer needed. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Severeside effectsmay end up causing a lot of disruption in a persons life. Available for Android and iOS devices. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. 3 0 obj Phosphorus is an electrolyte that your body needs in order to make energy. What is the latest research on the form of cancer Jimmy Carter has? There are currently no generic forms of either drug. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Then the study was split into the following two groups, which are discussed below. Keep all regular medical and laboratory appointments. pain in the arms or legs. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. However, many people have no side effects or only have minor side effects. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. FG Trade/E+ sia Getty Images You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. They can recommend if this is safe for you to do. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. You should always consult your doctor or another healthcare professional before taking any medication. This medication is given by injection into a vein as directed by your doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Venofer Side Effects. Nausea. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. After the infusion, you can drive yourself home and return to your usual activities. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and * Sex and gender exist on spectrums. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. chest pain. "That's why it's so . Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. We cancelled my 5th because of the reaction. Blood tests may be needed to check for unwanted effects. For people with certain medical implants, such as pacemakers, an MRI may pose an . Tell your doctor if you are pregnant or plan to become pregnant. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. . Instead, youll start by receiving just one treatment course of Injectafer. Many people using this medication do not have serious side effects. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Injectafer begins working as soon as it enters your body. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. This treatment course is split into two doses of the drug, which are given at least 7 days apart. This may be helped by giving the medication more slowly or at a lower dose. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Talk with your doctor. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. The following information is provided for clinicians and other healthcare professionals. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. They can recommend appropriate treatment options. <> But so far I feel better than before the infusion. This includes your doctors, nurses, pharmacists, and dentists. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. This gives a total cumulative dose of 1,500 mg of Injectafer. Heres some detail on certain side effects this drug may cause. I used to get a different type but my . Follow all instructions closely. You may report side effects to FDA at 1-800-FDA-1088. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Hemoglobin is a protein thats found inside your red blood cells. Then your body uses that iron to make hemoglobin and RBCs. Heart failure: Could a low sodium diet sometimes do more harm than good? Its not currently available in generic form. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. It is given into a vein for a period of time. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Iron infusion benefits. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. Its possible to get rid of or reduce the severity ofside effects. Its because everyones body is different. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. These side effects may include constipation and diarrhea. With this condition, you also have a low hemoglobin level. These side effects can range from being mild to severe. Pain in your limbs. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Tell your doctor if you are taking iron supplements or other iron-based oral medications. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . Injectafer helps to treat IDA by providing an iron infusion directly into your body. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Details. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Your doctor will be able to see how Venofer is working by reviewing your blood tests. This means you would get two Injectafer doses of 720 mg each. dizziness. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Can poor sleep impact your weight loss goals? Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. 1 0 obj Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Be ready to tell or show what was taken, how much, and when it happened. Others last much longer (even a lifetime), which can be quite traumatizing to people. But its not known whether this poses any risk to a child whos breastfed. Generics tend to cost less than brand-name drugs. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Its responsible for carrying oxygen throughout your body. But for other people, their anemia may come back after Injectafer treatment. No, you wont need to take iron pills while youre using Injectafer. In the second group, some people switched from taking iron by mouth to taking Injectafer. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. endobj Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. This is not a list of all drugs or health problems that interact with this medicine. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Depending on your anemia symptoms, your weight changes may be different than those described here. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. What are the side effects of Venofer? stream Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. (And Injectafer is used to treat IDA.) Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). You should not receive Venofer if you have known allergies to iron sucrose. endobj The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. Before using, check this product visually for particles or discoloration. cough. 2. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. There have also been reports of serious allergic reactions to Venofer. But for other people, doing so could lead to having too much iron in their body. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Its not known how often people taking a treatment other than Injectafer had diarrhea. Venofer is used to treat iron deficiency anemia in people with kidney disease. Orofer S 50 Injection 1 Injection in 1 Packet 147. How long does iron infusion stay in your system? Below are examples of these side effects. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Some may be a better fit for you than others. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Do not double the dose to catch up. This may lead to the person needing a higher dose compared to someone who is muchsmaller. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. (IV iron is absorbed by the body more rapidly than oral iron.) People in the study received treatment with either Injectafer or Venofer. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. This website is intended for use by US patients. Effectiveness of Injectafer compared with iron thats taken by mouth. It belongs to a class of medications called iron replacement products. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Serious side effects from Injectafer arent common, but they can occur. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. But the length of time that this may take varies from person to person. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. 2005 - 2023 WebMD LLC. Selected from data included with permission and copyrighted by First Databank, Inc. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. Together, you and your doctor can develop a treatment plan thats best for you. %PDF-1.3 Venofer may reduce the absorption of iron preparations taken by mouth. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. Here are answers to some frequently asked questions about Injectafer. The following information describes dosages that are commonly used or recommended. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Its possible that after getting two doses of Injectafer, your anemia may go away completely. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Venofer® (iron sucrose injection, USP) is available by prescription only. Some people only need one treatment course of Injectafer. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. Here we look at how Injectafer and Feraheme are alike and different. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. It may also cause nervousness, restlessness, and difficulty sleeping in some people. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. Following an LSD trip, users may experience a sort of 'comedown.'. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. A shortage of iron can cause health problems. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Answer by DrLact: About Venofer usage in lactation. So we cant say for sure whether the drug is safe to use while youre pregnant. You may need extra iron because of blood loss during kidney dialysis. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. (For more information on Venofer, see the Injectafer vs. Venofer section above). The Injectafer dosage your doctor prescribes will depend on your body weight. Your healthcare provider will watch you closely for 30 minutes after each dose. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Low blood pressure. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Find out what health conditions may be a health risk when taken with Venofer Vial These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Your doctor will go over your experience severe side effects, please seek medical attention right away and notify the ordering physician. Use Venofer as ordered by your doctor. Pain, swelling, or redness at the injection site may occur. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. Side effects like nausea and low blood pressure are common with most iron infusions. fever. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Best food forward: Are algae the future of sustainable nutrition? Learn more about these, as well as the symptoms, diagnosis, and treatments. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away.
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